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K5Cre;C/EBPαfl/fl mice are more susceptible to carcinogen-induced skin tumor development involving oncogenic Ras. A, tumor incidence and multiplicity (n = 13 mice/group).B, representative appearance of mice at 14 wks. C, immunoblot analysis of epidermal C/EBPα. D, activating Ras mutations were identified in codon 61 (CAA→CTA).
