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. 2013 Sep 7;3(9):e003554. doi: 10.1136/bmjopen-2013-003554

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Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/3.0/

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(A–F) The mean Sharp van der Heijde total Score from baseline to 1, 2, 5 and 8 years in patients in sustained remission, intermittent remission or never in remission by DAS28 Cr (A), DAS28-3 Cr (B), Boolean Cr (C), Boolean-3 Cr (D), SDAI Cr (E), SDAI-4 Cr (F). At baseline, there was a statistically significant difference overall only for DAS28-3 Cr, p=0.002 (Kruskal-Wallis test). At the follow-up visits, there was a statistically significant difference overall with p<0.001 between remission groups except for the Boolean Cr at 1 year, p=0.046, at 2 years, p=0.002 and at 8 years, p=0.013 and for the SDAI Cr at 1 year, p=0.011 and at 8 years, p=0.008.