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. Author manuscript; available in PMC: 2013 Sep 16.
Published in final edited form as: Biomaterials. 2009 Jan 26;30(12):2164–2174. doi: 10.1016/j.biomaterials.2008.12.084

Fig.1.

Fig.1

Methods of biomechanical testing of tissue spheroids: a) tensiometry: experimental device and changing shape of tissue spheroid before (A) and after (B) tissue compression; b) aspiration assay; c) fluorescent microbead assay; d) SEM of elastic scaffold for tensile testing; e) fused tissue spheroids attached to elastic scaffold; f) tensile testing using tissue construct fabricated from fused tissue spheroids; g) example of force–displacement relationship for tissue construct fabricated from fused tissue spheroids; h) envelopment assay – initial step of tissue spheroid fusion; i) fusion of tissue spheroid with equal level of cohesion; j) fusion of tissue spheroid with different levels of tissue cohesion – lower cohesive tissue spheroid (green) is enveloping more cohesive tissue spheroid (red).