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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Microvasc Res. 2013 Jun 24;89:172–175. doi: 10.1016/j.mvr.2013.06.008

Figure 1. Automated segmentation results of a nCPM.

Figure 1

A healthy subject was imaged with RFI, and an nCPM was created (A). To segment the capillary perfusion pattern, the order of gray scale in the image was inverted (B), and non-uniform illumination was corrected (C). After the removal of the background noise and non-vessel structures using a morphological opening operation the vessel network was segmented (D). The image was then skeletonized (E) for fractal analysis. The macular area (in the yellow circle with a diameter of 2.3 mm) was extracted (F) for fractal analysis. Bar = 1 mm.