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. 2013 Aug 26;110(37):15061–15066. doi: 10.1073/pnas.1307855110

Fig. 3.

Fig. 3.

Diversity and richness of skin microbiota decreases when C5aR signaling is inhibited. (A) The mean Shannon diversity index, a measure of α-diversity that takes into account OTU richness and evenness, was used to compare skin microbiota before treatment (BL) to C5aRA- and iC5aRA-treated skin microbiota. Higher Shannon diversity index indicates higher diversity. (B) Mean number of species-level OTUs observed before treatment (BL) and following treatment with C5aRA or iC5aRA. Error bars represent SEM (n = 14 mice for each group over two independent experiments; *P = 0.037 and **P = 0.005).