Fig. 2.

Export of nitrogen oxides (nitrite and nitrate) from human RBCs (n = 6; A and B) following incubation with vehicle or nor-NOHA in the presence of l-arginine. Nitrate in human blood (n = 9; C) incubated with vehicle, nor-NOHA, or nor-NOHA + l-NAME in the absence of l-arginine. Nitrate export from RBCs of wild-type and eNOS^−/− mice (n = 5; D) following incubation with vehicle or nor-NOHA with l-arginine. Data are shown as mean ± SEM. Significant differences from vehicle treatments are shown; *P < 0.05, **P < 0.01, ***P < 0.001 (one-way ANOVA).