Table 1.
Characteristics of diet-induced obese Rhesus Macaques.
| High fat fructose diet (n=6) | Chow (n=20) | |
|---|---|---|
| Body weight (kg) | 17.1±0.9 | 11.6±0.5⁎⁎⁎ |
| Lean mass (kg) | 10.5±1.4 | 8.9±0.3⁎⁎⁎ |
| Fat mass (kg) | 5.7±1.1 | 2.4±0.3⁎⁎⁎ |
| Trunk fat (%) | 41.7±5.2 | 21.9±2.0⁎⁎⁎ |
| BMC (g) | 466.9±70.2 | 439.3±10.4 |
| BMD (g/cm2) | 0.616±0.058 | 0.600±0.010 |
| Food intake (kCal/day) | 2323±223 | 718±25.7⁎⁎⁎ |
| Glucose (mg/dL) | 54.8±1.87 | 54.4±1.29 |
| Insulin (mIU/l) | 46.5±11.5 | 20.9±3.29⁎ |
| GTT-Glucose AUC | 12,034±484 | 9411±319⁎⁎⁎ |
| GTT-Insulin AUC | 16,539±4633 | 7681±1066⁎ |
| HbA1c (%) | 6.00±0.20 | 6.29±0.22 |
| HOMA-IR | 6.12±1.4 | 2.78±0.4⁎⁎ |
| VLDL particles (nM) | 48.6±3.06 | 3.6±1.08⁎⁎⁎ |
| Triglycerides (mg/dL) | 52.2±7.6 | 33.2±1.2⁎⁎⁎ |
| Cholesterol (mg/dL) | 196.8±20.1 | 110.0±4.5⁎⁎⁎ |
| HDL-C (mg/dL) | 104±13.1 | 70±3.8⁎⁎ |
Comparison of body weight, food intake, body composition and serum chemistry between diet-induced obese Rhesus Macaques and regular chow-fed Rhesus Macaques. Values represent the mean±SEM. Analysis ANOVA with Bonferroni posthoc.
⁎
p<0.05.
⁎⁎
p<0.01.
⁎⁎⁎
p<0.001 denotes significant difference from HFFD.