Table 3.

Associations of SNPs and ANCA-Associated Vasculitis, According to Clinical Syndromes Stratified on the Basis of ANCA Specificity.

Chromosome	Locus	SNP	Granulomatosis with Polyangiitis						Microscopic Polyangiitis
			Proteinase 3 vs. Myeloperoxidase (N = 1433 vs. 151)		Proteinase 3 vs. Control (N = 1433 vs. 6858)		Myeloperoxidase vs. Control (N = 151 vs. 6858)		Proteinase 3 vs. Myeloperoxidase (N = 75 vs. 366)		Proteinase 3 vs. Control (N = 75 vs. 6858)		Myeloperoxidase vs. Control (N = 366 vs. 6858)
			odds ratio	P value	odds ratio	P value	odds ratio	P value	odds ratio	P value	odds ratio	P value	odds ratio	P value
6	HLA–DP	rs3117242	5.24	4.9×10−24	7.51	3.7×10−86	1.60	9.2×10−2	2.76	6.9×10−4	2.49	9.8×10−5	1.50	1.4×10−1
6	HLA–DQ	rs5000634	1.46	3.1×10−2	0.86	7.8×10−5	0.62	2.1×10−5	1.34	6.9×10−1	0.79	4.7×10−1	0.68	1.4×10−5
6	ARHGAP18	rs1705767	0.77	3.7×10−1	0.72	2.2×10−7	NA	1.0×10−1	1.13	6.8×10−1	1.13	2.6×10−1	0.76	6.8×10−3
14	SERPINA1	rs7151526	0.63	1.9×10−1	0.52	1.2×10−10	0.72	4.3×10−1	0.37	2.8×10−3	0.31	1.5×10−5	0.78	9.8×10−1
19	PRTN3	rs62132295	0.61	2.3×10−3	0.73	3.9×10−7	1.22	2.2×10−1	0.60	1.1×10−1	0.65	1.3×10−1	1.03	7.7×10−1
X	MOSPD2	rs6628825	0.77	2.1×10−1	0.79	1.4×10−6	NA	9.8×10−1	0.62	7.2×10−2	0.31	5.4×10−3	0.87	5.4×10−1