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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Pharm Res. 2013 Jun 13;30(8):1947–1955. doi: 10.1007/s11095-013-1036-1

Figure 2. NTX plasma profiles following one-time MN treatment and application of diclofenac and NTX gel every 48 hours for 7 days post-MN.

Figure 2

NTX was detected to the end of the study for all subjects in Group 1 (MN + diclofenac + NTX, n = 6), with a mean AUC0 – 174 hr of 196.5 ± 37.7 ng•h/ml, which correlated with the impedance measurements that predicted micropore lifetime for approximately 3 – 7 days with application of diclofenac. Conversely, NTX was only detected until 72 hours in Group 2 (MN + placebo + NTX, n = 1).