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Number of micropores created for each treatment group and the gels applied to the skin.
| Group | Total number of micropores | Gels applied | In vitro flux of NTX•HCl, nmol/cm2•hr | Predicted [NTX], plasma (ng/ml) | Actual [NTX], plasma (ng/ml) | Actual [NTX] + [NTXol], plasma (ng/ml) |
|---|---|---|---|---|---|---|
| 1 | 800 (8 patches) | Diclofenac + NTX | 42.58 ± 7.88 (n = 3) | 4 | 1.2 (0.3) | 3.18 (0.7) |
| 2 | 200 (2 patches) | Placebo + NTX | 170.84 ± 32.12 (n = 3) | 4 | 1.1 | 1.19 |
| 3 | NA | Diclofenac + NTX | NA | 0 | 0 | 0 |
