. Author manuscript; available in PMC: 2014 Sep 1.

Published in final edited form as: Am J Kidney Dis. 2013 Jun 5;62(3):541–548. doi: 10.1053/j.ajkd.2013.03.039

Table 2.

Adjusted Mean PCS score by eGFR category

eGFR category	Model 1	Model 2	Model 3	Model 4	Model 5
≥90 mL/min/1.73 m² ^{^}	44.04 (43.39–44.68)	45.75 (44.98, 46.53)	43.97 (43.11, 44.83)	44.16 (43.31, 45.0)	43.37 (42.35, 44.39)
75–89 mL/min/1.73 m²	44.97 (44.43, 45.51)^*	46.19 (45.51, 46.87)	44.73 (43.95, 45.51)	44.54 (43.78, 45.30)	43.72 (42.83, 44.62)
60–74 mL/min/1.73 m²	45.00 (44.49, 45.51)^*	46.43 (45.75, 47.11)	44.88 (44.12, 45.64)	44.86 (44.11, 45.61)	44.02 (43.14, 44.91)
45–59 mL/min/1.73 m²	42.32 (41.66, 42.97)^*	44.02 (43.21, 44.82)^*	43.07 (42.19, 43.96)	43.37 (42.50, 44.24)	42.82 (41.82, 43.83)
30–44 mL/min/1.73 m²	40.41 (39.39, 41.42)^*	42.55 (41.41, 43.69)^*	42.21 (40.98, 43.43)^*	43.00 (41.78, 44.22)	43.40 (42.01, 44.79)
≤29 mL/min/1.73 m²	40.02 (38.20, 41.85)^*	41.22 (39.24, 43.19)^*	40.93 (38.73, 43.14)^*	42.56 (40.37, 44.75)	43.27 (41.02, 45.53)

Indicates statistical significance (p<0.05) compared to the reference group.

^{^}

Reference.

Note: Values are given as mean PCS score (95% confidence interval). Multivariable linear models included the following: in model 1, unadjusted regression analysis; in model 2, patient demographics (age, gender, race/ethnicity, marital status, household income, and education level); in model 3, additional adjustment for demographics and obesity, duration of diabetes and proteinuria; in model 4, fully-adjusted, including medical conditions and cardiovascular comorbidities: cerebrovascular disease, myocardial infarction, peripheral vascular disease, and coronary heart failure; and in model 5, mediation model with additional adjustment for baseline hemoglobin value.

PCS, physical component summary; eGFR, estimated glomerular filtration rate;