Table 3.
Adjusted Mean MCS score by eGFR category
| eGFR category | Model 1 | Model 2 | Model 3 | Model 4 | Model 5 |
|---|---|---|---|---|---|
| ≥90 mL/min/1.73 m2^ | 50.71 (50.18, 51.24) | 51.23 (50.58, 51.88) | 50.91 (50.15, 51.68) | 50.96 (50.20, 51.72) | 50.48 (49.54, 51.41) |
| 75–89 mL/min/1.73 m2 | 51.32 (50,88, 51.77) | 51.06 (50.49, 51.64) | 50.90 (50.21, 51.59) | 50.80 (50.12, 51.49) | 50.64 (49.82, 51.47) |
| 60–74 mL/min/1.73 m2 | 51.47 (51.05, 51.89)* | 51.25 (50.68, 51.83) | 50.50 (49.82, 51.17) | 50.44 (49.77, 51.12) | 50.41 (49.60, 51.22) |
| 45–59 mL/min/1.73 m2 | 50.90 (50.36, 51.45) | 50.57 (49.88, 51.24) | 50.58 (49.80, 51.37) | 50.77 (49.99, 51.56) | 50.99 (50.07, 51.91) |
| 30–44 mL/min/1.73 m2 | 51.04 (50.21, 51.88) | 51.10 (50.14, 52.07) | 50.65 (49.56, 51.74) | 51.19 (50.10, 52.28) | 51.50 (50.22, 52.77) |
| ≤29 mL/min/1.73 m2 | 48.18 (46.68, 49.68)* | 48.12 (46.45, 49.78)* | 47.52 (45.56, 49.48)* | 48.58 (46.61, 50.54)* | 49.04 (46.98, 51.11) |
Indicates statistical significance (p<0.05) compared to the reference group.
Reference.
Note: Values are given as mean MCS score (95% confidence interval). Multivariable linear models included the following: in model 1, unadjusted regression analysis; in model 2, patient demographics (age, gender, race/ethnicity, marital status, household income, and education level); in model 3, additional adjustment for demographics and obesity, duration of diabetes and proteinuria; in model 4, fully-adjusted, including medical conditions and cardiovascular comorbidities: cerebrovascular disease, myocardial infarction, peripheral vascular disease, and coronary heart failure; and in model 5, mediation model with additional adjustment for baseline hemoglobin value.
MCS, mental component summary; eGFR, estimated glomerular filtration rate;