Major Characteristics |
Pruritus |
Eczematoid rash on face and/or extensors in young children |
Lichenification in flexural areas in older children and adults |
Chronic or chronically relapsing dermatitis |
Personal or family history of atopic disease such as food allergy, asthma, allergic rhinitis |
Other Findings |
Dryness of skin and barrier dysfunction |
Allergic shiners (darkening beneath the eyes) |
Keratosis pilaris |
Ichthyosis vulgaris |
Hyperlinearity of palms and soles |
Elevated serum immunoglobulin E |
Immediate skin test reactivity to allergens |
Recurrent bacterial and viral skin infections |