Table 2. List of genes and number of polymorphisms evaluated.
| Genes catalyze androgens and estrogens synthesis and bioactivation |
Genes catalyze the synthesis of catecholestrogens |
Genes metabolically inactive androgen and estrogens |
|||
|---|---|---|---|---|---|
|
| |||||
| Gene | No. of polymorphisms |
Gene | No. of polymorphisms |
Gene | No. of polymorphisms |
| AKR1C1 | 4 | CYP1A1 | 3 | SULT1A1 | 2 |
| AKR1C2 | 7 | CYP1B1 | 5 | SULT1E1 | 6 |
| AKR1C3 | 5 | CYP3A4 | 4 | SULT2A1 | 4 |
| AKR1C4 | 8 | UGT2B15 | 3 | ||
| COMT | 6 | UGT2B17 | 4 | ||
| CYP11A1 | 4 | UGT2B28 | 2 | ||
| CYP17A1 | 4 | UGT2B4 | 5 | ||
| CYP19A1 | 6 | UGT2B7 | 3 | ||
| HSD17B1 | 3 | ||||
| HSD17B2 | 4 | ||||
| HSD17B3 | 8 | ||||
| HSD17B4 | 5 | ||||
| HSD17B7 | 6 | ||||
| HSD17B12 | 8 | ||||
| HSD3B1 | 7 | ||||
| HSD3B2 | 3 | ||||
| SRD5A1 | 6 | ||||
| SRD5A2 | 5 | ||||
| STS | 3 | ||||
|
| |||||
| Total: | 143 | ||||