Skip to main content
. Author manuscript; available in PMC: 2014 Aug 8.
Published in final edited form as: J Med Chem. 2013 Jul 22;56(15):6108–6121. doi: 10.1021/jm400823w

Table 4.

Biodistribution of [99mTc]L15 in tumor-bearing mice.a

30 min 1 h 2 h 5 h

blood 0.53 ± 0.15 0.54 ± 0.07 0.24 ± 0.35 0.19 ± 0.25
heart 0.72 ± 0.23 0.72 ± 0.09 0.17 ± 0.11 0.23 ± 0.06
lung 2.83 ± 0.81 2.59 ± 0.80 1.58 ± 0.45 1.80 ± 0.14
liver 0.62 ± 0.23 0.39 ± 0.05 0.26 ± 0.09 0.24 ± 0.07
stomach 1.01 ± 0.83 1.56 ± 0.65 1.40 ± 0.92 0.45 ± 0.23
pancreas 1.23 ± 0.56 2.36 ± 2.43 0.54 ± 0.20 0.55 ± 0.09
spleen 24.05 ± 9.01 25.66 ± 4.99 7.55 ± 2.14 10.10 ± 2.34
fat 0.85 ± 0.60 1.45 ± 0.44 0.10 ± 0.19 0.35 ± 0.61
kidney 242.68 ± 36.55 346.60 ± 28.12 270.08 ± 44.35 261.65 ± 26.90
muscle 0.83 ± 0.54 0.86 ± 0.02 0.13 ± 0.31 0.34 ± 0.12
sml. intetine 0.46 ± 0.07 0.53 ± 0.36 0.20 ± 0.18 0.38 ± 0.18
lrg intestine 0.48 ± 0.04 0.47 ± 0.21 0.06 ± 0.12 0.25 ± 0.05
bladder 1.09 ± 0.43 1.24 ± 0.86 0.25 ± 0.47 2.42 ± 1.41
PC3 PIP 20.52 ± 2.12 23.44 ± 3.82 18.27 ± 3.35 28.01 ± 5.81
PC3 flu 0.41 ± 0.06 0.43 ± 0.09 0.29 ± 0.13 0.38 ± 0.19
PIP: flu 48.18 ± 7.67 57.40 ± 7.12 70.14 ± 24.93 92.48 ± 40.51
PIP: blood 42.49 ± 21.24 42.57 ± 11.64 67.0328 ± 0.00 63.08 ± 19.84
PIP: muscle 63.69 ± 80.92 18.65 ± 16.57 73.65 ± 0.00 85.42 ± 27.06
a

Values expressed are in % ID/g ± standard deviation. N = 4 for all tissues