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Hypo-IRAS rats exhibit increases in anxiety-like behaviors in the elevated plus maze. Compared to hypo-Con rats, hypo-IRAS rats exhibited significant decreases in percentage of open arm entries (Panel A). These decreases in open arm behaviors were not the result of decreased locomotor activity since the distance traveled in the elevated plus maze did not differ between the groups (Panel B). [* = p<0.02 compared to hypo-Con rats; data based upon at least 10 rats/group]
