Table 1.
Rate of appearance and first pass extraction of selected amino acids in piglets during fasting and fed conditions
| Fasted, μmol·kg−1·h−1 | Fed, μmol·kg−1·h−1 | P | FPE, % | |
|---|---|---|---|---|
| RaPhe* | 132 ± 7.0 | 173 ± 9.2 | <0.0001 | |
| RaTyr | 121 ± 7.7 | 209 ± 11.5 | <0.0001 | |
| RaCit | 75 ± 6.9 | 74 ± 6.7 | <0.432 | |
| RaOrn | 73 ± 1.9 | 91 ± 6.9 | <0.0001 | |
| RaArg | 293 ± 32.9 | 366 ± 56.1 | <0.0001 | 12.9 ± 2.0 |
| RaPro | 184 ± 10.1 | 313 ± 21.5 | <0.0001 | 28.1 ± 5.0 |
| RaGln | 810 ± 85.9 | 1,028 ± 94.2 | <0.0001 | 64.3 ± 3.7 |
Values are means ± SE; n = 6 experiments, except for ornithine (Orn), citrulline (Cit), phenylalanine (Phe), and tyrosine (Tyr) rate of appearance (Ra) where n = 18. FPE, first pass splanchnic extraction, calculated from the disappearance of the ig tracer with respect to the iv infused tracer. Arg, arginine; Pro, proline; Gln, glutamine.
*
Rate of appearance, calculated from the isotopic dilution of the iv infused tracer.