Table 1.
Current genomewide large-scale ENU mouse mutagenesis projects
| Project | Screen Type | Phenotype | Website | References |
|---|---|---|---|---|
| Australian Phenomics Facility | Recessive | Immunology Hearing Male fertility Gastrointestinal tract | http://www.apf.edu.au/about/projects/ | 22, 34, 66 |
| Genomics Institute of the Novartis Research Foundation | Dominant and Recessive | Immunology Neurobiology Vision Metabolic disorders Hearing | http://www.gnf.org/technology/organismal/mammalian-genetics-phenotyping.htm | 38 |
| MRC Harwell Mutagenesis Project | Dominant and Recessive | All Major Physiological Systems | http://www.har.mrc.ac.uk/research/mutagenesis/ | 20, 21, 74 |
| Munich ENU Project | Dominant and Recessive | Dysmorphology Allergy Metabolic disorders Aldosterone | http://www.helmholtz-muenchen.de/en/ieg/group-functional-genetics/enu-screen/index.html | 3, 4, 68 |
| The Scripps Research Institute | Dominant and Recessive | All major physiological systems | http://mutagenetix.scripps.edu/home.cfm | 7, 8, 50 |
| The Jackson Laboratory | Recessive | All major physiological systems | http://research.jax.org/collaboration/index.html | 12, 19, 36, 62 |
| RIKEN ENU Mutagenesis Project | Dominant and Recessive | All major physiological systems | http://www.brc.riken.jp/lab/gsc/mouse/ | 30, 59, 70 |
A summary of large-scale N-ethyl-N-nitrosourea (ENU) mutagenesis projects that have published mutations in the past 24 mo. This table does not claim to be complete.