FIGURE 3.

Frequencies of T cells expressing the anti-K^b TCR protein in IMA and NIMA mice. The expression of the anti-K^b TCR Tg protein on the surface of peripheral blood CD3⁺CD8⁺ T cells was assessed by FACS analysis using the anti-clonotypic mAb, Ti98. Representative FACS pro-files obtained with control non-Tg CBA mice (A), control anti-K^b TCR Tg Bm3.3 mice (B), IMA offspring that inherited both the anti-K^b TCR and the K^b protein (C), and NIMA mice that inherited the anti-K^b TCR transgene but not the K^b transgene (D). The results are representative of >100 mice in each group.