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. Author manuscript; available in PMC: 2013 Sep 16.
Published in final edited form as: J Immunol. 2010 Dec 22;186(3):1442–1449. doi: 10.4049/jimmunol.1003023

FIGURE 4.

FIGURE 4

Fetal and neonatal NIMA-exposed T cells are partially deleted from the thymus. Thymus T cells from NE or NIMA mice were analyzed by flow cytometry, using the Ti98 mAb specific for the BM3.3 Tg TCR. A, Compilation of cell numbers (± SEM) of BM3.3 Tg thymic T cells from NE control, NIMA, or IMA animals as 16.5- and 18.5-d pc fetuses, newborns, or 3.5-d-old neonates; at least seven animals were studied in each group in three separate experiments. *p,<0.05; **p,<0.01. B, Flow cytometry profiles obtained from NE or NIMA BM3.3 Tg thymic T cells from 18.5-d pc fetuses and 3.5-d-old neonates, after per-meabilization and staining with propidium iodide (PI). Percentages of cells in G0/G1 or S/G2/M phases of the cell cycle are given in each graph. One experiment representative of at least three for each group is shown.