Table 2.
Findings on exercise and pharmacologic stress and myocardial perfusion imaging dichotomized by presence or absence of chest pain or shortness of breath
| Characteristic | Exercise Stress (n=200) | Pharmacologic Stress (n=375) | ||||
|---|---|---|---|---|---|---|
| Symptomatic (n (%)) |
Asymptomatic (n(%)) |
P-value | Symptomatic (n(%)) |
Asymptomatic (n(%)) |
P-value | |
| Total patients | 163 | 37 | 246 | 129 | ||
| METS achieved (median (25th 75th percentiles)* | 8.0 (6.6, 10.0) | 8.6 (7.0, 10.1) | 0.61 | Not applicable. | ||
| ≥10 METS achieved* | 37 (23.1) | 7 (58.3) | 0.007 | |||
| Peak exercise heart rate | 144 (133, 157) | 140 (132, 151) | 0.31 | |||
| Maximum systolic BP* | 199 (180, 222) | 204 (178, 223) | 0.64 | |||
| Maximum diastolic BP* | 85 (75, 97) | 89 (73, 100) | 0.49 | |||
| Chest pain during stress | 23 (14.1) | 1 (2.7) | 0.054 | |||
| ≥1mm stress ST-depression | 19 (11.7) | 7 (18.9) | 0.28 | 8 (3.2) | 5 (3.9) | 0.77 |
| LVEF* | 63 (59, 67) | 62 (58, 67) | 0.28 | 63 (54, 68) | 63 (54, 68) | 0.73 |
| LVEF<45%* | 8 (4.9) | 5 (13.5) | 0.068 | 25 (10.2) | 7 (5.4) | 0.12 |
| ESV index ≥25 mL/m2 *,† | 19 (12.0) | 8 (22.9) | 0.11 | 44 (18.0) | 29 (22.7) | 0.28 |
| Summed stress score | 0.023 | 0.51 | ||||
| 0–3 | 142 (87.1) | 26 (70.3) | 202 (82.1) | 109 (84.5) | ||
| 4–8 | 9 (5.5) | 6 (16.2) | 16 (6.5) | 10 (7.8) | ||
| >8 | 12 (7.4) | 5 (13.5) | 28 (11.4) | 10 (7.8) | ||
| Summed rest score | 0.084 | 0.51 | ||||
| 0–3 | 154 (94.5) | 33 (89.2) | 219 (89.0) | 119 (92.3) | ||
| 4–8 | 7 (4.3) | 1 (2.7) | 13 (5.3) | 6 (4.7) | ||
| >8 | 2 (1.2) | 3 (8.1) | 14 (5.7) | 4 (3.1) | ||
*
BP=blood pressure; ESV=end-systolic volume; LVEF=left-ventricular ejection fraction; METS=metabolic equivalents.
†
End-systolic volume indexis missing in 3asymptomatic and 5 symptomatic patients in the exercise cohort and 1 asymptomatic and 1 symptomatic patient in the pharmacologic cohort.