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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: J Immunol. 2013 Aug 7;191(6):3254–3263. doi: 10.4049/jimmunol.1300722

Figure 7. Effect of priming with [PspA] beads and PPS14+[PspA] beads in the PspA- and PPS14-specific IgG responses to PPS14+[PspA] beads.

Figure 7

Groups of five naïve BALB/c mice (PBS) and mice previously immunized with ≈2×108 beads coated only with PspA ([PspA] beads; 167 ng per dose) 14 days earlier (d-14), were immunized at days 0 and 17 with 174 ng of PspA in the form of beads coated only with PspA ([PspA] beads) or with beads coated simultaneously with PspA and PPS14 (PPS14+[PspA] beads, admixed with CpG-ODN without alum. *p < 0.05 (Each group relative to the responses of naïve mice to the immunization with PPS14+[PspA] beads at days 0 and 17), #p < 0.05 (titer−1 relative to the previous bleeding in each mouse group).