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. Author manuscript; available in PMC: 2013 Oct 3.
Published in final edited form as: Cell Metab. 2012 Oct 3;16(4):526–537. doi: 10.1016/j.cmet.2012.09.007

Figure 3. SKN-1 Is Activated by Starvation and Changes in Available Nutrients.

Figure 3

(A) GO-terms of genes identified as dysregulated by transcriptional analysis of the lax120 and lax188 mutants.

(B) SKN-1 activity sensor worms were grown on food or under starvation conditions and then imaged for GFP expression indicative of SKN-1 activation of the gst-4p::gfp reporter. (C) Quantification of GFP levels observed as described in (B).

(D–I) Indicated strains were fed the E. coli B strain OP50.

(D)–(F) or the E.coli K12 strain HT115 (G)–(I) and imaged for GFP expression as described in (B).