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MMP-13 and membrane type (MT)-1-MMP levels were determined by immunoblotting on LV myocardial extracts taken from young WT (n = 14) and old (n = 12) WT and young (n = 12) and old (n = 17) EMMPRINexp mice. There were no changes in relative MMP-13 levels between groups. However, MT1-MMP myocardial levels were significantly increased in the EMMPRINexp mice. P < 0.05 *vs. young WT; #vs. old WT.
