Fig. 7.

Representative LV sections taken from WT (n = 3) and EMMPRINexp old (n = 6) mice, which were stained using a selective human EMMPRIN antisera. In WT and negative control sections (Neg Control), a complete absence of positive EMMPRIN staining was observed. However, in EMMPRINexp sections, a specific immunoreactive signal was detected along the sarcolemmal surface of myocytes (arrows). At high power (top right), EMMPRIN immunostaining could be appreciated to localize to the sarcolemmal-interstitial interface (arrows). Scale bar = 20 μm.