Table 3.
Femoral biomechanical properties as determined by three-point bending following 21 days of Mars-analog loading in female mice
Baseline | Age | Jacket | Mars | |
---|---|---|---|---|
n | 8 | 19 | 7–8 | 7–9 |
Stiffness, N/mm | 125.85 ± 12.10 | 136.05 ± 10.13‡ | 113.76 ± 19.21§ | 114.70 ± 13.86* |
Yield moment, N·mm | 15.69 ± 5.56 | 17.33 ± 4.50 | 11.11 ± 4.39§ | 13.05 ± 1.21* |
Ultimate moment, N·mm | 26.10 ± 3.59 | 29.10 ± 3.90 | 22.94 ± 5.89§ | 21.20 ± 3.38* |
Postyield bending work, N·mm | 5.45 ± 2.16 | 5.51 ± 1.71 | 5.81 ± 1.86 | 5.67 ± 2.22 |
Estimated Young's modulus, N/mm2 | 5,611.95 ± 598.13 | 5,584.61 ± 580.81 | 4,641.47 ± 580.42§ | 5,480.99 ± 702.87† |
Values are means ± SD; n, no. of mice.
Mars significantly different than Age,
Mars significantly different than Jacket,
Age significantly different than Baseline, and
Jacket significantly different than Age: P < 0.05.