Fig. 5.

Unaltered Ca²⁺ handling in control rats, SHR, and Iso-treated rats. A: representative superimposed recording of cell length and intracellular Ca²⁺ concentration transients (CaiT) from isolated myocytes of control rats (black trace) and SHR (red trace). The contraction amplitude and the CaiT amplitude under field-stimulated conditions (0.5 Hz) or under caffeine pulse (25 mmol/l) were not different between the strains. ΔFFI, change in Fura 2 fluorescence intensity. B: average data of these experiments. C: mean values of these parameters comparing control with Iso-rats. There were no significant differences in any of the variables studied between SHR or Iso-rats with respect to their controls. Values are means ± SE; n, no. of myocytes in each experimental group (in parentheses).