. Author manuscript; available in PMC: 2013 Sep 16.

Published in final edited form as: J Am Chem Soc. 2009 Mar 11;131(9):3377–3384. doi: 10.1021/ja809580b

Table 2.

HC50 and Hill Coefficients for All Mst Peptides with and without Added Metal

peptide/metal	HC50 (μM)	n	fold increase in toxicity
Mastoparan X (apo)	119 ± 4	1.6 ± 0.1
Mst-HH:
apo	295 ± 17	1.4 ± 0.1
300 μM Zn(II) added	38 ± 2	1.9 ± 0.2	8
300 μM Ni(II) added	33 ± 2	1.3 ± 0.1	9
Mst-EH:
apo*	250 ± 28	2.2 ± 0.6
300 μM Zn(II) added	81 ± 3	2.1 ± 0.1	3
300 μM Ni(II) added	273 ± 6	2.2 ± 0.1
Mst-HAH:
apo	69 ± 5	1.9 ± 0.2
300 μM Zn(II) added	119 ± 10	1.0 ± 0.1
300 μM Ni(II) added	6.7 ± 0.7	1.8 ± 0.7	10