Table 4.
Comparison of NEFA model parameters and indices obtained by analysis of data from IVGTT, OGTT, and meal tolerance tests in normal human subjects
| IVGTT, Boston and Moate, 2008 | OGTT, This Analysis | MT, This Analysis | |
|---|---|---|---|
| Parameters | |||
| Gb, mmol/l | 4.83–4.89 | 4.45–5.26 | 4.42–5.66 |
| NEFA0, μmol/l | 415–570 | 212.4–573.5 | 478.4–678.5 |
| R0, mmol/l | 0.05–0.57 | 0–0.41 | 0–0.13 |
| kC, %/min | 2.25–3.59 | 2.31–6.34 | 1.71–5.44 |
| SFFA, μmol·l−1·min−1 | 40.3–64.7 | 29.6–161 | 6.6–70.1 |
| KFFA, %/min | 5.4–12.9 | 4.7–12.6 | 1.39–12.1 |
| gs, mmol/l | 4.3–5.7 | 4.2–5.7 | 4.2–6.6 |
| Φ, mmol/l | 0.26–0.81 | 0.11–0.25 | 0.05–0.33 |
| Indices | |||
| LIP0, μmol·l−1·min−1 | 24.2–36.4 | 12.6–161 | 6.6–70.1 |
| OX0, μmol·l−1·min−1 | 24.7–53.6 | 16.2–71.5 | 9.5–57.7 |
| NTLR0, μmol·l−1·min−1 | −18.2–1.7 | −4.9–89.2 | −6.7–58.1 |
| NEFAmin, μmol/l | 54.1–179.3 | 33.9–75.1 | 96.4–219.8 |
| Tmin, min−1 | 46–73 | 93–112 | 127–784 |
| Suppression, % | 60.5–90.6 | 83.1–89.8 | 62.2–81.8 |
| RMSE | <12 | 11.8–24.8 | 31.7–75.3 |
| Adjusted R2 | ≥0.99 | 0.98–0.99 | 0.61–0.97 |
Values are expressed as ranges. IVGTT, intravenous glucose tolerance test.