Table 1.

Data collection and refinement statistics (values in parentheses are for highest-resolution shell). See Table S4 for crystallization methods, conditions and data collection source and molecular replacement (MR) searching model.

Protein name	LPBCA	LECA	AECA	LACA	LAFCA	LGPCA	LBCA
PDB identifier	2YJ7	2YOI	3ZIV	2YNX	2YPM	2YN1	4BA7
Data collection
Space Group	P 1 21 1	C 1 2 1	P 1 21 1	P 1	P 21 21 21	P 1 21 1	F 4 3 2
Cell dimensions a, b, c (Å)	55.1, 30.2, 59.0	58.4, 47.8, 73.8	37.6, 48.8, 91.1	32.2, 36.3, 48.1	37.5, 42.8, 55.9	36.1 62.9 42.9	192.7
β (°)	117.0	98.5	93.2	108.0	90.0	109.0	90.0
ASU	2	2	3	2	1	2	2
Resolution (Å) *	48.45 – 1.65 (1.74 – 1.65)	36.6 – 1.30 (1.37 – 1.30)	45.51 – 2.65 (2.74 – 2.65)	45.32 – 1.75 (1.84 – 1.75)	20.00 – 2.20 (2.28 – 2.20)	34.09 – 1.30 (1.35 – 1.30)	58.10 – 2.45 (2.53 – 2.45)
Rsym (%)*	4.5 (34.1)	4.7 (6.6)	6.5 (59.9)	10.5 (39.6)	10.3 (48.7)	5.6 (42.8)	13.0 (93.4)
I/σI *	20.10 (3.80)	18.40 (7.90)	16.21 (3.24)	8.50 (2.70)	23.26 (4.95)	12.47 (2.68)	12.92 (4.18)
Completeness (%)*	99.8 (100.0)	94.4 (89.8)	97.8 (97.9)	97.6 (88.7)	99.0 (100.0)	97.2 (97.7)	99.9 (100.0)
Unique reflections*	21198 (712)	46574	9592	18887	4904	43308	11808
Multiplicity*	3.6 (3.7)	2.0 (1.8)	4.0 (4.0)	1.0 (2.9)	10.4 (10.7)	2.8 (2.8)	7.7 (8.0)
Refinement
Resolution (Å)	48.45 – 1.65	36.6 – 1.30	45.51 – 2.65	45.32 – 1.75	20.00 – 2.20	34.09 – 1.30	58.10 – 2.45
Rwork/Rfree (%)	18.19/21.98	15.43/18.47	18.22/27.39	15.76/21.52	16.65/23.92	16.76/20.42	15.83/21.08
No. atoms	2117	4371	2390	3934	918	4121	3764
Protein	1852	1926	2382	1817	866	1825	1819
Water	264	433	8	184	52	357	69
Ligands	1	7	0	2	0	2	8
Average B-factors (Å2)	21.80	16.20	80.00	19.80	31.00	18.30	44.20
R.m.s deviations
Bond lengths (Å)	0.007	0.011	0.008	0.013	0.009	0.011	0.015
Bond angles (°)	0.97	1.29	1.15	1.39	1.09	1.35	1.48
Ramachandran (%)
Favored	100.0	98.0	96.0	98.0	99.0	99.0	100.0
Outliers	0.0	0.0	0.0	0.0	0.0	0.0	0.0