. Author manuscript; available in PMC: 2013 Sep 16.

Published in final edited form as: Eur J Pharmacol. 2004 Jan 12;483(0):289–293. doi: 10.1016/j.ejphar.2003.10.045

Table 2.

D₅₀ ± S.E.M. values for GHB and haloperidol, given after 0.32 mg/kg dizocilpine or vehicle, to produce catalepsy (n = 9 for each pretreatment and treatment combination)

Pretreatment	Treatment	D₅₀ (mg/kg), i.p.
Pretreatment	Treatment	Bar test	Hindlimb test
Dizocilpine Vehicle	GHB	345.1 ± 24.5	338.7 ± 23.8
	GHB	589.5 ± 14.9	551.8 ± 9.11
	Potency ratio	1.7 (1.4–2.1)	1.6 (1.3–2.0)
Dizocilpine Vehicle	Haloperidol	>0.56	>0.56
	Haloperidol	0.20 ± 0.019	0.23 ± 0.029
	Potency ratio	>2.8	>2.4

The ratios of the D₅₀ values obtained after pretreatment with dizocilpine or vehicle differed significantly from 1 because their 95% confidence limits (indicated between parentheses) did not contain 1.