Table 3.

Changes in psychosocial scale scores by study group.

		Study Visit Means ± SD
Variable	Study Group	Baseline	6 Months	12 Months	Change, Baseline to 12 Months (95% CI)*	P Value for Trend Within Group	P Value for group difference in trend
Anger-in	CRM	14.4 (3.9)	14.1 (3.8)	13.7 (3.4)	-0.35 (-1.69, 0.99)	0.60	0.71
	HE	14.0 (4.0)	13.4 (3.5)	13.3 (3.6)	0.0002 (-1.33, 1.33)	1.00
Anger-out	CRM	12.9 (3.4)	12.2 (3.2)	13.4 (3.7)	0.34 (-0.76, 1.45)	0.54	0.52
	HE	13.0 (2.5)	13.5 (3.2)	12.4 (2.5)	-0.17 (-1.27, 0.93)	0.76
Hostility	CRM	17.2 (8.1)	17.6 (8.0)	17.7 (8.0)	1.69 (-0.46, 3.84)	0.12	0.10
	HE	18.0 (7.4)	16.7 (8.4)	15.4 (6.7)	-0.84 (-2.98, 1.30)	0.44
PSS	CRM	14.8 (8.4)	14.0 (6.9)	12.1 (6.2)	-1.66 (-4.42, 1.11)	0.24	0.022
	HE	17.4 (8.6)	14.0 (7.7)	9.4 (6.4)	-6.50 (-9.55, -3.45)	<0.001
STAI-State	CRM	36.8 (13.2)	32.4 (10.1)	28.4 (7.7)	-6.63 (-10.73, -2.53)	0.002	0.65
	HE	40.0 (14.1)	35.8 (11.0)	31.7 (7.6)	-8.01 (-12.40, -3.62)	0.001
STAI-Trait	CRM	38.2 (11.9)	34.4 (11.1)	33.4 (8.7)	-2.43 (-5.22, 0.37)	0.088	0.48
	HE	39.5 (12.4)	37.7 (13.5)	33.2 (8.6)	-3.88 (-6.87, -0.88)	0.012
BDI-Somatic	CRM	0.6 (0.4)	0.5 (0.3)	0.3 (0.2)	-0.19 (-0.34, -0.05)	0.011	0.72
	HE	0.6 (0.5)	0.5 (0.4)	0.4 (0.4)	-0.16 (-0.31, -0.01)	0.040
BDI-Cognitive	CRM	2.6 (3.1)	1.7 (2.1)	0.6 (0.8)	-1.34 (-2.48, -0.21)	0.021	0.87
	HE	3.3 (3.9)	2.6 (3.5)	1.2 (1.6)	-1.47 (-2.61, -0.34)	0.011
BDI-Total	CRM	10.9 (7.7)	7.8 (5.4)	5.1 (3.3)	-3.76 (-6.38, -1.15)	0.005	0.86
	HE	11.0 (9.7)	9.0 (7.8)	6.1 (6.0)	-3.44 (-6.04, -0.84)	0.010

^*Model estimates, adjusted for individual variance, obtained using repeated measures mixed effects models.

PSS: Perceived Stress Scale; STAI: State-Trait Anxiety Inventory; BDI: Beck Depression Inventory.