Table 4.

Effects of angiotensin II, PD-123319, and losartan on action potential characteristics of pooled ischemic endocardium and Purkinje tissues

	AGII (n = 21)			PD (n = 12)			Losartan (n = 10)
	Baseline	AGII	P Value	Baseline	PD	P Value	Baseline	Losartan	P Value
RMP, mV	−81±3	−81±3	NS	−77±3	−78±5	NS	−92±4	−88±2	NS
APA, mV	87±3	84±4	NS	83±5	82±6	NS	94±5	90±5	NS
APD50, ms	172±9	172±11	NS	188±13	192±13	NS	188±14	179±13	NS
APD90, ms	258±11	247±11	NS	256±15	258±14	NS	247±16	233±14	NS

Values are means ± SE;

n, no. of animals. RMP, resting membrane potential; APA, action potential amplitude; APD₅₀, action potential duration at 50% amplitude; APD₉₀, action potential duration at 90% amplitude.