Figure 7.

Destruction of cells expressing or lacking α-gal epitopes by the ADCC mechanism with mouse splenocytes as effector cells and with mouse anti-Gal (4 μg/mL). Target cells studied are: BL6_{α GT} melanoma cells expressing α-gal epitopes (filled triangles); BL6 cells lacking α-gal epitopes (open triangles); COS_{α GT} monkey cells expressing α-gal epitope (filled squares); COS cells lacking α-gal epitopes (open squares); pig PK15 cells (filled diamonds). Data are representative from 1 of 5 mice with similar results.