TABLE 2.
B16F10L-luciferase day 17
Shown are quantitative RT-PCR results of candidate genes expressed in F4/80+ (TAMS) immunopurified from day 17 primary subcutaneous melanoma tumors, as described under “Experimental Procedures.”
| M1 immune stimulatory | M2 immune suppressive | F4/80+ (TAMs) A1Tg+/+/A1KO RQ (95% CI) |
|---|---|---|
| ↑ Ifng | 24.3 (22.1–26.7) | |
| ↑ Ccl22 | 5.44 (5.08–5.83) | |
| ↑ Il6 | 2.82 (2.68–2.96) | |
| ↑ Nos2 | 2.16 (2.01–2.33) | |
| ↑ Cx3cl1 | 2.12 (1.97–2.29) | |
| ↑ Il12b | 1.85 (1.76–1.94) | |
| ↑ Il1b | 1.80 (1.72–1.89) | |
| ↑ Cc17 | 1.36 (1.36–1.37) | |
| ↑ Cxcl10 | 1.27 (1.25–1.28) | |
| ↓ Pparg | 0.57 (0.56–0.58) | |
| ↓ Il10 | 0.66 (0.61–0.73) | |
| ↓ Chi313 | 0.78 (0.76–0.80) | |
| ↑ Arg1 | 2.31 (2.26–2.37) |