Fig. 1.

Spleen tyrosine kinase (Syk) inhibitor therapy attenuates ischemia-reperfusion (I/R) injury in the intestine. A: representative hematoxylin and eosin (H & E)-stained slides from the intestine of mice subjected to I/R or sham operation and treated with R788 (3 g/kg and 5 g/kg for 6 days) were visualized and captured under a light microscope. Each image is representative of 3 mice/group. All photomicrographs are ×200 magnification. B: H & E-stained intestinal sections from different treatment groups were scored for intestinal mucosal damage as described in materials and methods. Each bar is the average ± SE for 3 mice/group.