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. 2012 Nov 30;304(3):H415–H426. doi: 10.1152/ajpheart.00468.2012

Fig. 2.

Fig. 2.

Nampt+/− hearts are protected from agonist-induced hypertrophy. A: cardiac Nampt levels in the wild-type (WT) control and Nampt+/− mice. B: HW-to-BW ratio of control and Nampt+/− mice infused with either vehicle (Veh) or isoproterenol (Iso) for 7 days. NS, not significant. C: Masson's trichrome-stained heart sections from WT and Nampt+/− mice infused with Iso. D and E: echocardiographic measurements of left ventricular wall thickness and fractional shortening of control and Nampt+/− mice. F: β-MHC Col1a1 and α-SMA mRNA levels in the heart samples of Iso infused or untreated WT and Nampt+/− mice. Means ± SD; n = 6. *Statistically significant.