Fig. 6.

Annotation of locations: We identified the location of local maxima of Von Mises stresses (Fig. 5) according to several anatomic criteria, denoted here. Peak stresses were either identified as being located on a thin fibrous cap over a lipid-rich core or plaque shoulders, the two locations where plaque rupture are known to occur in human lesions, or on the media or adventitia or elsewhere in the plaque.