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Effect of the LO inhibitor NDGA on arachidonic acid relaxations of mouse mesenteric arteries. Relaxation responses of arteries preconstricted with phenylephrine [vehicle control (●) or 10 μM NDGA (○)] or U46619 [vehicle control (▼) or 10 μM NDGA (△)]. Each value represents the mean ± SE; n = 8–10. *P < 0.05 compared with vehicle control (U46619-preconstricted arteries).
