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Effect of K+ channel inhibition on 12(S)-HETE relaxations in mouse mesenteric arteries preconstricted with U46619. The arteries were pretreated with apamin (SKCa blocker, 1 μM; A), iberiotoxin (BKCa blocker, 100 nM; B), and apamin plus TRAM-34 (IKCa blocker, 1 μM; C). Each value represents the mean ± SE; n = 4–12.
