Table 2.
Comparisons of serum surrogate markers for cardiovascular disease between those with normal and poor endothelial function
| Normal Endothelial Function | Abnormal Endothelial Function | P Value | |
|---|---|---|---|
| Humanin, ng/ml | 2.2 (±1.5) | 1.3 (±1.1) | 0.03∗ |
| Insulin, micro-IU/ml | 6.2 (±4.6) | 5.8 (±3.9) | 0.79 |
| Glucose, mg/dl | 118.7 (±89.2) | 96.9 (±9.8) | 0.28 |
| Hemoglobin A1c, % | 5.3 (±0.7) | 5.2 (±0.3) | 0.46 |
| l-Arginine, ng/ml | 63.7 (±16.6) | 71.0 (±17.1) | 0.18 |
| hs-CRP, mg/l | 1.5 (±1.9) | 1.6 (±2.3) | 0.80 |
| Homocysteine, μmol/l | 8.0 (±2.3) | 8.0 (±2.6) | 0.95 |
| Hemoglobin, ×1012/l | 14.3 (±1.1) | 14.2 (±1.6) | 0.90 |
| Leukocytes, ×109/l | 7.2 (±0.4) | 6.0 (±1.4) | 0.03∗ |
| Neutrophils, ×109/l | 4.2 (±1.6) | 3.7 (±1.2) | 0.29 |
| Monocytes, ×109/l | 0.6 (±0.2) | 0.4 (±0.2) | 0.03∗ |
| Lymphocytes, ×109/l | 2.1 (±0.6) | 1.6 (±0.6) | 0.02∗ |
| Platelets, ×109/l | 261.3 (±96.1) | 252.6 (±64.7) | 0.74 |
| Uric acid, mg/dl | 4.9 (±1.9) | 4.6 (±1.6) | 0.53 |
| BNP, pg/ml | 20.5 (±11.2) | 29.7 (±43.3) | 0.36 |
| Fibrinogen, mg/dl | 259.4 (±68.9) | 279.6 (±73.4) | 0.37 |
| Total cholesterol, mg/dl | 190.1 (±55.2) | 189.3 (±46.5) | 0.96 |
| LDL-cholesterol, mg/dl | 108.4 (±47.8) | 114.0 (±39.2) | 0.68 |
| HDL-cholesterol, mg/dl | 53.6 (±15.4) | 52.6 (±9.5) | 0.81 |
| Triglycerides, mg/dl | 140.6 (±76.0) | 115.3 (±15.2) | 0.27 |
Values are means (±SD). hs-CRP, high-sensitivity C-reactive protein; BNP, brain natriuretic peptide.
∗
Significant difference.