Table 2.
Baseline hemodynamics: before vs. after bed rest following dextran infusion
| Pre | Post | % Change | P Value | Interaction P Value | |
|---|---|---|---|---|---|
| ExDex (n = 7) | |||||
| MBP, mmHg | 83 ± 3 | 82 ± 2 | −0.7 ± 2.0 | 0.659 | 0.183 |
| Qc, liter | 7.1 ± 0.4 | 7.5 ± 0.3 | 8.6 ± 7.5 | 0.367 | 0.704 |
| SV, ml | 106 ± 6 | 112 ± 8 | 6.1 ± 4.0 | 0.151 | 0.883 |
| TPR, dyn·s·cm−5 | 959 ± 66 | 881 ± 33 | −5.8 ± 6.9 | 0.302 | 0.900 |
| PCWP, mmHg | 11.2 ± 0.8 | 11.5 ± 0.8 | 3.0 ± 3.3 | 0.391 | 0.200 |
| RAP, mmHg | 7.7 ± 0.7 | 7.6 ± 0.4 | 1.8 ± 6.9 | 0.846 | 0.275 |
| LVEDV, ml | 129 ± 9 | 144 ± 9 | 13.3 ± 3.9 | 0.015* | 0.012* |
| SedDex (n = 7) | |||||
| MBP, mmHg | 85 ± 2 | 88 ± 3 | 3.3 ± 1.9 | 0.131 | |
| Qc, liter | 7.4 ± 0.2 | 8.2 ± 0.2 | 11.8 ± 3.4 | 0.011* | |
| SV, ml | 113 ± 7 | 118 ± 5 | 5.4 ± 2.4 | 0.054* | |
| TPR, dyn·s·cm−5 | 936 ± 39 | 869 ± 26 | −6.8 ± 2.0 | 0.019* | |
| PCWP, mmHg | 10.2 ± 0.6 | 11.0 ± 0.5 | 8.8 ± 2.7 | 0.009* | |
| RAP, mmHg | 6.6 ± 0.7 | 7.2 ± 0.5 | 11.9 ± 5.6 | 0.094 | |
| LVEDV, ml | 140 ± 7 | 138 ± 11 | −2.3 ± 3.6 | 0.669 | |
Values are means ± SE. ExDex, exercise + dextran; SedDex, sedentary + dextran. Pre vs. Post was compared with paired t-tests, and % changes were compared with unpaired t-test for interaction between groups.
*
P < 0.05.