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. Author manuscript; available in PMC: 2013 Oct 26.
Published in final edited form as: Science. 2013 Apr 26;340(6131):471–475. doi: 10.1126/science.1231031

Fig. 4. Progressive cardiomyopathy of Mfn2-deficient mouse hearts and Parkin-deficient Drosophila heart tubes.

Fig. 4

(A) Transmission electron microscopic examination of mouse cardiomyocyte mitochondria (5,000x). (B) Whole cell O2 consumption studies of cadiomyocytes isolated from wild-type (black) or Mfn2-deficient (red) mouse hearts. (C) M-mode echocardiograms of mouse hearts. (D) Confocal imaging of Drosophila cardiomyocyte mitochondria. (E) O2 consumption studies of heart tubes isolated from wild-type (black) or Parkin-deficient (red) Drosophila. (F) Optical coherence tomography of Drosophila heart tubes. (G) Mitochondrial ubiquitination (green) induced by FCCP in wild-type and Parkin-deficient Drosophila cardiomyocytes.