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. Author manuscript; available in PMC: 2014 Aug 15.
Published in final edited form as: J Immunol. 2013 Jul 12;191(4):2009–2017. doi: 10.4049/jimmunol.1301317

Figure 3. CD8+ T cells restrain NSCLC growth in CC10-TAg mice.

Figure 3

(A) H&E staining of lungs from CC10-TAg mice deficient for selective lymphocyte subsets. (B) Quantification of tumor burden from mice shown in A. n=4∓5 mice per group. (C) Survival of CC10-TAg mice compared with those deficient in CD8+ T lymphocytes. p<0.0001; n=30 mice per group. (D) Tumor burden quantified as percentage of lung area in CC10-TAg mice following CD8+ T cell depletion from 8 weeks until 12 weeks of age. n=3∓7 mice per group, with one of three representative experiments shown. *p<0.05; **p<0.01, ***p<0.001.

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