Figure 5.
Population differences in log2 fold change tend to reflect stronger responses in EA. a) Histogram showing the distribution of population differences in absolute value of the log2 fold change for the 177 genes with significant inter-ethnic differences. Negative values on the x-axis indicate a stronger response in EAs. The red vertical line marks the position of GIMAP5 in the distribution. b) As an example of a biologically relevant gene with population differences in response, the distribution of log2 fold change in EAs and AAs is shown for GIMAP5, a known regulator of lymphocyte proliferation.