Table 2.
Comprehensive list of all regions-of-interest assessed and the calculated probability values for each main effect and interaction from the 2×2×2 ANOVA on the cytochrome oxidase imaging data. Regions showing significant (*p< 0.05) main effects and interactions were assessed with post hoc 2-tailed t-tests
| ROI | Genotype (G) | Diet (D) | Sex (S) | G×D | S×G | S×D | S×G×D |
|---|---|---|---|---|---|---|---|
| Optic tract (opt) | 0.751 | 0.280 | 0.172 | 0.916 | 0.105 | 0.649 | 0.611 |
| Cingulate gyrus, retrosplenial (RSG) | 0.028* | 0.539 | 0.376 | 0.648 | 0.909 | 0.350 | 0.058 |
| Cingulate gyrus, posterior 2 (CGp2) | 0.418 | 0.661 | 0.086 | 0.690 | 0.269 | 0.505 | 0.655 |
| Cingulate gyrus, posterior (CGp) | 0.105 | 0.001* | 0.380 | 0.006* | 0.298 | 0.829 | 0.635 |
| Cingulate gyrus, middle (CGm) | 0.063 | 0.225 | 0.211 | 0.606 | 0.571 | 0.433 | 0.947 |
| Cingulate gyrus, anterior (CGa) | 0.102 | 0.375 | 0.074 | 0.321 | 0.772 | 0.654 | 0.927 |
| Posterior parietal cortex (PPtA) | 0.139 | 0.951 | 0.058 | 0.754 | 0.562 | 0.691 | 0.554 |
| Lateral entorhinal cortex (LEnt) | 0.026* | 0.316 | 0.560 | 0.394 | 0.689 | 0.008* | 0.620 |
| Primary somatosensory cortex (S1) | 0.062 | 0.022* | 0.389 | 0.018* | 0.443 | 0.789 | 0.785 |
| Primary somatosensory, BF (S1BF) | 0.046* | 0.066 | 0.225 | 0.289 | 0.909 | 0.857 | 0.512 |
| Secondary somatosensory cortex (S2) | 0.090 | 0.064 | 0.149 | 0.173 | 0.780 | 0.767 | 0.913 |
| Primary auditory cortex (Au1) | 0.020* | 0.522 | 0.100 | 0.821 | 0.453 | 0.508 | 0.916 |
| Primary visual, monocular (V1) | 0.002* | 0.737 | 0.302 | 0.986 | 0.299 | 0.989 | 0.025* |
| Piriform cortex (Pir) | 0.841 | 0.862 | 0.350 | 0.764 | 0.648 | 0.805 | 0.171 |
| CA1 (CA1) | 0.002* | 0.542 | 0.571 | 0.742 | 0.321 | 0.617 | 0.009* |
| CA3 (CA3) | 0.005* | 0.119 | 0.327 | 0.676 | 0.003* | 0.989 | 0.018* |
| Dentate gyrus (DG) | 0.170 | 0.348 | 0.526 | 0.125 | 0.743 | 0.242 | 0.008* |
| Subiculum (S) | 0.001* | 0.606 | 0.061 | 0.451 | 0.673 | 0.491 | 0.279 |
| Medial mammillary nucleus (M) | 0.869 | 0.359 | 0.563 | 0.505 | 0.251 | 0.275 | 0.008* |
| Substantia nigra (SNR) | 0.131 | 0.964 | 0.273 | 0.600 | 0.457 | 0.019* | 0.730 |
| Basolateral amygdala (BLA) | 0.372 | 0.056 | 0.262 | 0.168 | 0.924 | 0.938 | 0.882 |
| Anteroventral thalamus (AV) | 0.958 | 0.828 | 0.779 | 0.517 | 0.485 | 0.398 | 0.623 |
| Reticular thalamus (Rt) | <0.001* | 0.149 | 0.367 | 0.402 | 0.471 | 0.553 | 0.013* |
| Reuniens nucleus (Re) | 0.639 | 0.461 | 0.278 | 0.778 | 0.479 | 0.897 | 0.436 |
| Ventromedial thalamus (VM) | 0.296 | 0.127 | 0.137 | 0.188 | 0.965 | 0.688 | 0.693 |
| Ventrolateral thalamus (VL) | 0.023* | 0.021* | 0.090 | 0.175 | 0.965 | 0.570 | 0.600 |
| Mediodorsal thalamus (MD) | 0.116 | 0.009* | 0.438 | 0.053 | 0.362 | 0.148 | 0.585 |
| Laterodorsal thalamus (LD) | 0.051 | 0.391 | 0.267 | 0.614 | 0.311 | 0.150 | 0.073 |
| Lateral posterior thalamus (LP) | 0.599 | 0.010* | 0.620 | 0.183 | 0.375 | 0.088 | 0.593 |
| Parafascicular thalamus (PF) | 0.112 | 0.792 | 0.062 | 0.823 | 0.462 | 0.695 | 0.268 |
| Ventroposterolateral thalamus (VPL) | 0.230 | 0.183 | 0.609 | 0.400 | 0.710 | 0.919 | 0.153 |
| Ventroposteromedial thalamus (VPM) | 0.168 | 0.677 | 0.057 | 0.629 | 0.368 | 0.763 | 0.346 |
| Posterior thalamus (Po) | 0.155 | 0.310 | 0.227 | 0.539 | 0.777 | 0.731 | 0.372 |
| Lateral habenula (LHb) | 0.806 | 0.683 | 0.450 | 0.380 | 0.935 | 0.454 | 0.448 |
| Rostral caudoputamen (rCPu) | 0.181 | 0.018* | 0.269 | 0.837 | 0.539 | 0.755 | 0.735 |
| Caudal caudoputamen (cCPu) | 0.021* | 0.790 | 0.224 | 0.360 | 0.643 | 0.991 | 0.242 |
| Lateral globus pallidus (LGP) | 0.228 | 0.706 | 0.301 | 0.928 | 0.797 | 0.963 | 0.999 |
| Subthalamus (STh) | 0.269 | 0.366 | 0.099 | 0.689 | 0.276 | 0.909 | 0.727 |
| Nucleus accumbens (Acb) | 0.742 | 0.216 | 0.318 | 0.869 | 0.384 | 0.668 | 0.592 |
| Nuc. of vertical diagonal band (VDB) | 0.409 | 0.205 | 0.303 | 0.277 | 0.875 | 0.514 | 0.749 |
| Medial septal nucleus (MS) | 0.936 | 0.246 | 0.170 | 0.376 | 0.803 | 0.840 | 0.947 |
| Lateral septal nucleus (LSI) | 0.100 | 0.096 | 0.183 | 0.893 | 0.872 | 0.990 | 0.883 |
| Nucleus basalis (B) | 0.043* | 0.099 | 0.333 | 0.389 | 0.325 | 0.235 | 0.162 |
| Anterior hypothalamus (AH) | 0.337 | 0.634 | 0.063 | 0.708 | 0.150 | 0.602 | 0.935 |
| Lateral hypothalamus (LH) | 0.387 | 0.004* | 0.478 | 0.436 | 0.935 | 0.737 | 0.699 |
| Dorsolateral geniculate (DLG) | 0.196 | 0.291 | 0.102 | 0.839 | 0.443 | 0.366 | 0.360 |
| Medial geniculate (MG) | <0.001* | 0.354 | 0.008* | 0.080 | 0.236 | 0.022* | 0.499 |
| Superior colliculus (SC) | 0.001* | 0.281 | 0.052 | 0.120 | 0.516 | 0.055 | 0.968 |
| Pontine nuclei (PnC) | 0.111 | 0.394 | 0.598 | 0.362 | 0.744 | 0.826 | 0.132 |
| Inferior colliculus, central (CIC) | 0.267 | 0.051 | 0.500 | 0.420 | 0.278 | 0.365 | 0.003* |
| Periaqueductal gray (PAG) | 0.114 | 0.226 | 0.975 | 0.938 | 0.523 | 0.405 | 0.091 |
| Vestibular nuclei (Ve) | 0.956 | 0.048* | 0.950 | 0.614 | 0.299 | 0.936 | 0.222 |
| Reticular nucleus, giganto (Gi) | 0.605 | 0.095 | 0.633 | 0.930 | 0.958 | 0.258 | 0.865 |
| Cerebellar lobules 1–5 (Cb) | 0.008* | 0.763 | 0.133 | 0.858 | 0.870 | 0.244 | 0.592 |
| Simple lobule (Sim) | 0.081 | 0.936 | 0.042* | 0.370 | 0.994 | 0.160 | 0.393 |
| Crus 1 lobule (Crus1) | 0.043* | 0.349 | 0.191 | 0.256 | 0.884 | 0.100 | 0.958 |