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. Author manuscript; available in PMC: 2013 Sep 16.
Published in final edited form as: Exp Neurol. 2010 Jul 15;225(2):341–352. doi: 10.1016/j.expneurol.2010.07.005

Figure 2.

Figure 2

Blood brain barrier (BBB) permeability measured via Evan's blue extravasation. BBB permeability measurement (mean absorbance/mg tissue) from homogenized cortical tissue derived from the hemisphere ipsilateral to CCI injury (n = 6/group). Increased BBB permeability is observed in normal rats after cortical injury with preservation towards uninjured levels with MAPC therapy. The same experiment completed in animals after splenectomy failed to show the increase in BBB permeability with cortical injury. Y axis represents mean absorbance normalized with mass of parenchymal tissue. * indicates statistical significance compared to CCI injury alone control sample (ANOVA with Tukey Kramer post hoc, p < 0.05).