Table 3.
Gene Ontology categories significantly enriched with differentially expressed genes
| GO Category | Total Genes on Array | Changed Genes | Enrichment | P Value | FDR | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Liver | ||||||||||
| Metabolic processes (GO:0008152) | 668 | 73↑ | 1.19 | 0.01 | 0.03 | |||||
| Protein biosynthesis (GO:0006412) | 109 | 28↑ | 2.88 | 0.00 | 0.00 | |||||
| Positive regulation of signal transduction (GO:0009967) | 13 | 6↑ | 5.04 | 0.00 | 0.00 | |||||
| Urea cycle (GO:0000050) | 2 | 2↓ | 22.35 | 0.00 | 0.28 | |||||
| Urea cycle intermediate metabolic process (GO:0000051) | 5 | 3↓ | 13.41 | 0.00 | 0.20 | |||||
| Muscle | ||||||||||
| Protein biosynthesis (GO:0006412) | 114 | 16↑ | 2.96 | 0.00 | 0.00 | |||||
| Amino acid transport (GO:0006865) | 5 | 2↑ | 8.44 | 0.02 | 0.63 | |||||
Arrows indicate direction of expression changes in hibernating black bears. GO, Gene Ontology; FDR, false discovery rate.