Table 3.

^†††: Plasma Half-Lives of WHO-recommended First and Second-Line Antiretroviral Therapy

Plasma Half-Lives (hours)
NRTIs
Lamivudine	5–9
Zidovudine	0.5–3
Emtricitabine	8–10
Tenofovir	12–15
NNRTIs
Efavirenz	40–100
Nevirapine	25–60
PIs
Atazanavir	4–24
Lopinavir	5–6
Ritonavir	3–8

^†††Abbreviations: NRTIs- nucleoside reverse transcriptase inhibitors, NNRTIs- non-nucleoside reverse transcriptase inhibitors, PIs - Protease Inhibitors.