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. 2013 Sep 16;8(9):e74168. doi: 10.1371/journal.pone.0074168

Table 3. Odds ratio (95% CI) and adjusted odds ratio (95% CI) of the metabolic syndrome and its components by sex- specific quartiles of serum ferritin.

Q1 Q2 Q3 Q4 P (trend)
Men
Ferrintin(mg/L) 51.9 97.2 154.0 422.5
MetS 1 1.43 (1.11-1.86) 1.75 (1.36-2.25) 3.75 (2.96-4.74) <0.001
model 1a 1.49 (1.15-1.93) 1.86 (1.44-2.39) 4.08 (3.21-5.19) <0.001
model 2b 1.49 (1.15-1.93) 1.86 (1.44-2.39) 4.05 (3.19-5.14) <0.001
Waist 1 1.12 (0.91-1.38) 1.62 (1.32-1.98) 2.46 (2.02-3.00) <0.001
model 1 1.16 (0.94-1.43) 1.70 (1.39-2.08) 2.63 (2.16-3.21) <0.001
model 2 1.15 (0.94-1.42) 1.69 (1.38-2.07) 2.60 (2.13-3.18) <0.001
TG 1 1.49 (1.20-1.85) 2.22 (1.80-2.73) 4.16 (3.39-5.10) <0.001
model 1 1.48 (1.19-1.84) 2.18 (1.77-2.69) 4.09 (3.33-5.01) <0.001
model 2 1.47 (1.19-1.83) 2.17 (1.76-2.67) 4.06 (3.31-4.99) <0.001
HDL 1 1.30 (1.00-1.70) 1.56 (1.20-2.02) 2.60 (2.04-3.32) <0.001
model 1 1.30 (1.00-1.70) 1.60 (1.23-2.07) 2.65 (2.07-3.39) <0.001
model 2 1.30 (1.00-1.70) 1.60 (1.23-2.07) 2.64 (2.06-3.37) <0.001
BP 1 1.02 (0.85-1.22) 1.09 (0.91-1.30) 1.23 (1.03-1.47) <0.001
model 1 1.11 (0.92-1.34) 1.23 (1.02-1.48) 1.46 (1.21-1.76) <0.001
model 2 1.11 (0.92-1.34) 1.22 (1.01-1.47) 1.44 (1.19-1.74) 0.0013
GLU 1 1.34 (1.02-1.76) 1.53 (1.17-2.00) 2.48 (1.93-3.19) <0.001
model 1 1.42 (1.08-1.87) 1.66 (1.26-2.17) 2.82 (2.17-3.65) <0.001
model 2 1.43 (1.08-1.88) 1.67 (1.28-2.19) 2.82 (2.18-3.64) <0.001
Women
Ferrintin(mg/L) 12.9 36.0 68.4 142.7
MetS 1 1.58 (1.25-1.98) 2.52 (2.02-3.13) 4.92 (3.99-6.08) <0.001
model 1 1.25 (0.99-1.58) 1.48 (1.17-1.88) 2.43 (1.92-3.08) <0.001
model 2 1.25 (0.98-1.58) 1.46 (1.15-1.85) 2.34 (1.84-2.97) <0.001
Waist 1 1.22 (1.03-1.44) 1.82 (1.54-2.16) 2.74 (2.31-3.26) <0.001
model 1 1.01 (0.85-1.20) 1.17 (0.97-1.40) 1.45 (1.19-1.77) <0.001
model 2 1.01 (0.85-1.20) 1.16 (0.97-1.40) 1.44 (1.18-1.75) 0.0009
TG 1 1.53 (1.23-1.89) 2.13 (1.74-2.62) 3.96 (3.24-4.83) <0.001
model 1 1.38 (1.11-1.72) 1.69 (1.36-2.11) 2.87 (2.93-3.59) <0.001
model 2 1.38 (1.12-1.73) 1.69 (1.36-2.11) 2.86 (2.28-3.58) <0.001
HDL 1 1.15 (0.96-1.38) 1.17 (0.98-1.40) 1.62 (1.36-1.93) <0.001
model 1 1.15 (0.96-1.37) 1.16 (0.97-1.39) 1.60 (1.34-1.91) <0.001
model 2 1.15 (0.95-1.37) 1.15 (0.95-1.39) 1.55 (1.27-1.90) <0.001
BP 1 1.53 (1.26-1.84) 2.83 (2.36-3.40) 3.83 (3.20-4.60) <0.001
model 1 1.01 (0.82-1.24) 1.13 (0.92-1.40) 1.08 (0.87-1.34) 0.5824
model 2 1.01 (0.82-1.24) 1.14 (0.92-1.40) 1.08 (0.87-1.34) 0.5759
GLU 1 2.04 (1.46-2.87) 2.73 (1.97-3.78) 5.82 (4.28-7.91) <0.001
model 1 1.61 (1.14-2.27) 1.60 (1.13-2.27) 2.89 (2.06-4.06) <0.001
model 2 1.60 (1.14-2.27) 1.58 (1.12-2.24) 2.80 (1.99-3.93) <0.001

a: model 1, Odds ratio adjusted for age, nationality, smoking use, and alcohol consumption.

b: model 2, Odds ratio adjusted for model 1 plus hs-CRP.